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A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury

BACKGROUND: Hepatitis is a common adverse effect of antituberculosis drugs. Silymarin prevented drug-induced hepatoxicity in animals with anti-oxidative mechanisms but its effect in human has been unknown. We aimed to evaluate the efficacy of silymarin for preventing antituberculosis-drug induced li...

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Detalles Bibliográficos
Autores principales: Luangchosiri, Chote, Thakkinstian, Ammarin, Chitphuk, Sermsiri, Stitchantrakul, Wasana, Petraksa, Supanna, Sobhonslidsuk, Abhasnee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580123/
https://www.ncbi.nlm.nih.gov/pubmed/26400476
http://dx.doi.org/10.1186/s12906-015-0861-7