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Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord

BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...

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Detalles Bibliográficos
Autores principales: Charkhpour, Mohammad, Ghavimi, Hamed, Ghanbarzadeh, Saeed, Yousefi, Bahman, Khorrami, Arash, Mesgari, Mehran, Hassanzadeh, Kambiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580127/
https://www.ncbi.nlm.nih.gov/pubmed/26394827
http://dx.doi.org/10.1186/s12929-015-0187-2