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Protective effect of pioglitazone on morphine-induced neuroinflammation in the rat lumbar spinal cord
BACKGROUND: Morphine-induced tolerance is associated with the spinal neuroinflammation. The aim of this study was to explore the effects of oral administration of the pioglitazone, the peroxisome proliferator activated receptor gamma (PPAR-γ) agonist, on the morphine-induced neuroinflammation in the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580127/ https://www.ncbi.nlm.nih.gov/pubmed/26394827 http://dx.doi.org/10.1186/s12929-015-0187-2 |