Mitochondrial dysfunction in aging: Much progress but many unresolved questions

The free radical theory of aging is almost 60 years old. As mitochondria are the principle source of intracellular reactive oxygen species (ROS), this hypothesis suggested a central role for the mitochondrion in normal mammalian aging. In recent years, however, much work has questioned the importanc...

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Detalles Bibliográficos
Autores principales: Payne, Brendan A.I., Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580208/
https://www.ncbi.nlm.nih.gov/pubmed/26050973
http://dx.doi.org/10.1016/j.bbabio.2015.05.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580208/
https://www.ncbi.nlm.nih.gov/pubmed/26050973
http://dx.doi.org/10.1016/j.bbabio.2015.05.022

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