Analysis of the effect of the mitochondrial prohibitin complex, a context-dependent modulator of longevity, on the C. elegans metabolome()

The mitochondrial prohibitin complex, composed of two proteins, PHB-1 and PHB-2, is a context-dependent modulator of longevity. Specifically, prohibitin deficiency shortens the lifespan of otherwise wild type worms, while it dramatically extends the lifespan under compromised metabolic conditions. T...

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Detalles Bibliográficos
Autores principales: Lourenço, Artur B., Muñoz-Jiménez, Celia, Venegas-Calerón, Mónica, Artal-Sanz, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580209/
https://www.ncbi.nlm.nih.gov/pubmed/26092086
http://dx.doi.org/10.1016/j.bbabio.2015.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580209/
https://www.ncbi.nlm.nih.gov/pubmed/26092086
http://dx.doi.org/10.1016/j.bbabio.2015.06.003

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