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Analysis of the effect of the mitochondrial prohibitin complex, a context-dependent modulator of longevity, on the C. elegans metabolome()
The mitochondrial prohibitin complex, composed of two proteins, PHB-1 and PHB-2, is a context-dependent modulator of longevity. Specifically, prohibitin deficiency shortens the lifespan of otherwise wild type worms, while it dramatically extends the lifespan under compromised metabolic conditions. T...
Autores principales: | Lourenço, Artur B., Muñoz-Jiménez, Celia, Venegas-Calerón, Mónica, Artal-Sanz, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580209/ https://www.ncbi.nlm.nih.gov/pubmed/26092086 http://dx.doi.org/10.1016/j.bbabio.2015.06.003 |
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