Comparison of Hi-C results using in-solution versus in-nucleus ligation

BACKGROUND: Chromosome conformation capture and various derivative methods such as 4C, 5C and Hi-C have emerged as standard tools to analyze the three-dimensional organization of the genome in the nucleus. These methods employ ligation of diluted cross-linked chromatin complexes, intended to favor p...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagano, Takashi, Várnai, Csilla, Schoenfelder, Stefan, Javierre, Biola-Maria, Wingett, Steven W., Fraser, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580221/
https://www.ncbi.nlm.nih.gov/pubmed/26306623
http://dx.doi.org/10.1186/s13059-015-0753-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580221/
https://www.ncbi.nlm.nih.gov/pubmed/26306623
http://dx.doi.org/10.1186/s13059-015-0753-7

Ejemplares similares