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Comparison of Hi-C results using in-solution versus in-nucleus ligation

BACKGROUND: Chromosome conformation capture and various derivative methods such as 4C, 5C and Hi-C have emerged as standard tools to analyze the three-dimensional organization of the genome in the nucleus. These methods employ ligation of diluted cross-linked chromatin complexes, intended to favor p...

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Detalles Bibliográficos
Autores principales:	Nagano, Takashi, Várnai, Csilla, Schoenfelder, Stefan, Javierre, Biola-Maria, Wingett, Steven W., Fraser, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580221/ https://www.ncbi.nlm.nih.gov/pubmed/26306623 http://dx.doi.org/10.1186/s13059-015-0753-7

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