Significantly shorter Fe-S bond in cytochrome P450-I is consistent with greater reactivity relative to chloroperoxidase

Cytochrome P450 (P450) and chloroperoxidase (CPO) are thiolate ligated heme proteins that catalyze the activation of carbon hydrogen bonds. The principal intermediate in these reactions is a ferryl radical species called compound I. P450 compound I (P450-I) is significantly more reactive than CPO-I,...

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Detalles Bibliográficos
Autores principales: Krest, Courtney M., Silakov, Alexey, Rittle, Jonathan, Yosca, Timothy H., Onderko, Elizabeth L., Calixto, Julio C., Green, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580274/
https://www.ncbi.nlm.nih.gov/pubmed/26291940
http://dx.doi.org/10.1038/nchem.2306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580274/
https://www.ncbi.nlm.nih.gov/pubmed/26291940
http://dx.doi.org/10.1038/nchem.2306

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