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Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

AIM: IL-1β was considered as an important inflammatory cytokine in diabetic cardiovascular complications. DCM is one of the major manifestations of diabetic cardiovascular complications whose specific mechanisms are still unclear. In this study, we investigated the role of IL-1β in myocytes apoptosi...

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Detalles Bibliográficos
Autores principales: Liu, Zhongwei, Zhao, Na, Zhu, Huolan, Zhu, Shunming, Pan, Shuo, Xu, Jing, Zhang, Xuejun, Zhang, Yong, Wang, Junkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580368/
https://www.ncbi.nlm.nih.gov/pubmed/26394923
http://dx.doi.org/10.1186/s12933-015-0288-y