KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer

BACKGROUND: It is recognised that modulations of the nuclear import of macromolecules have a role in changing cellular phenotypes and carcinogenesis. We and others have noticed that aberrant subcellular localisation of DNA damage response (DDR) proteins in breast cancer (BC) is associated with loss-...

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Detalles Bibliográficos
Autores principales: Alshareeda, A T, Negm, O H, Green, A R, Nolan, C C, Tighe, P, Albarakati, N, Sultana, R, Madhusudan, S, Ellis, I O, Rakha, E A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580386/
https://www.ncbi.nlm.nih.gov/pubmed/25989275
http://dx.doi.org/10.1038/bjc.2015.165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580386/
https://www.ncbi.nlm.nih.gov/pubmed/25989275
http://dx.doi.org/10.1038/bjc.2015.165

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