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Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer

BACKGROUND: The objective of the study was to examine the role of microsatellite instability (MSI) and BRAF(V600E)mutation in colorectal cancer (CRC) by categorising patients into more detailed subtypes based on tumour characteristics. METHODS: Tumour samples from 762 population-based patients with...

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Detalles Bibliográficos
Autores principales: Seppälä, T T, Böhm, J P, Friman, M, Lahtinen, L, Väyrynen, V M J, Liipo, T K E, Ristimäki, A P, Kairaluoma, M V J, Kellokumpu, I H, Kuopio, T H I, Mecklin, J-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580394/
https://www.ncbi.nlm.nih.gov/pubmed/25973534
http://dx.doi.org/10.1038/bjc.2015.160