PTEN loss is associated with follicular variant of Middle Eastern papillary thyroid carcinoma

BACKGROUND: PTEN gene at chromosomes 10q23.3 is a tumour suppressor gene that is inactivated in many types of human cancers. The known mechanisms of PTEN inactivation are rendered to mutation, epigenetic silencing by aberrant methylation or gene deletion. Although PTEN role has been documented in ma...

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Detalles Bibliográficos
Autores principales: Beg, S, Siraj, A K, Jehan, Z, Prabakaran, S, Al-Sobhi, S S, Al-Dawish, M, Al-Dayel, F, Al-Kuraya, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580399/
https://www.ncbi.nlm.nih.gov/pubmed/25989274
http://dx.doi.org/10.1038/bjc.2015.169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580399/
https://www.ncbi.nlm.nih.gov/pubmed/25989274
http://dx.doi.org/10.1038/bjc.2015.169

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