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Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels

Scorpion toxins are important pharmacological tools for probing the physiological roles of ion channels which are involved in many physiological processes and as such have significant therapeutic potential. The discovery of new scorpion toxins with different specificities and affinities is needed to...

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Detalles Bibliográficos
Autores principales: ElFessi-Magouri, Rym, Peigneur, Steve, Othman, Houcemeddine, Srairi-Abid, Najet, ElAyeb, Mohamed, Tytgat, Jan, Kharrat, Riadh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580410/
https://www.ncbi.nlm.nih.gov/pubmed/26398235
http://dx.doi.org/10.1371/journal.pone.0137611