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Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?

Oxidative stress (OS)-induced senescence of the amniochorion has been associated with parturition at term. We investigated whether telomere fragments shed into the amniotic fluid (AF) correlated with labor status and tested if exogenous telomere fragments (T-oligos) could induce human and murine amn...

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Detalles Bibliográficos
Autores principales: Polettini, Jossimara, Behnia, Faranak, Taylor, Brandie D., Saade, George R., Taylor, Robert N., Menon, Ramkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580414/
https://www.ncbi.nlm.nih.gov/pubmed/26397719
http://dx.doi.org/10.1371/journal.pone.0137188