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The Relationship of Immune Cell Signatures to Patient Survival Varies within and between Tumor Types

Enhancing pre-existing anti-tumor immunity leads to therapeutic benefit for some patients, but why some tumors are more immunogenic than others remains unresolved. We took a unique systems approach to relate patient survival to immune gene expression in >3,500 tumor RNAseq profiles from a dozen t...

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Detalles Bibliográficos
Autores principales: Linsley, Peter S., Chaussabel, Damien, Speake, Cate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580625/
https://www.ncbi.nlm.nih.gov/pubmed/26398410
http://dx.doi.org/10.1371/journal.pone.0138726