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Transcriptome Profiling of Pediatric Core Binding Factor AML

The t(8;21) and Inv(16) translocations disrupt the normal function of core binding factors alpha (CBFA) and beta (CBFB), respectively. These translocations represent two of the most common genomic abnormalities in acute myeloid leukemia (AML) patients, occurring in approximately 25% pediatric and 15...

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Detalles Bibliográficos
Autores principales: Hsu, Chih-Hao, Nguyen, Cu, Yan, Chunhua, Ries, Rhonda E., Chen, Qing-Rong, Hu, Ying, Ostronoff, Fabiana, Stirewalt, Derek L., Komatsoulis, George, Levy, Shawn, Meerzaman, Daoud, Meshinchi, Soheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580636/
https://www.ncbi.nlm.nih.gov/pubmed/26397705
http://dx.doi.org/10.1371/journal.pone.0138782