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Pharmacokinetic Drug Interaction Studies with Enzalutamide

BACKGROUND AND OBJECTIVES: Two phase I drug interaction studies were performed with oral enzalutamide, which is approved for the treatment of metastatic castration-resistant prostate cancer (mCRPC). METHODS: A parallel-treatment design (n = 41) was used to evaluate the effects of a strong cytochrome...

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Detalles Bibliográficos
Autores principales: Gibbons, Jacqueline A., de Vries, Michiel, Krauwinkel, Walter, Ohtsu, Yoshiaki, Noukens, Jan, van der Walt, Jan-Stefan, Mol, Roelof, Mordenti, Joyce, Ouatas, Taoufik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580724/
https://www.ncbi.nlm.nih.gov/pubmed/25929560
http://dx.doi.org/10.1007/s40262-015-0283-1