Disinhibitory Action of Astrocytic GABA at the Perforant Path to Dentate Gyrus Granule Neuron Synapse Reverses to Inhibitory in Alzheimer's Disease Model

Like neurons, astrocytes produce and release GABA to influence neuronal signaling. At the perforant path to dentate gyrus granule neuron synapse, GABA from astrocyte was found to be a strong inhibitory factor, which impairs synaptic transmission, synaptic plasticity and memory in Alzheimer's di...

Descripción completa

Detalles Bibliográficos
Autores principales: Yarishkin, Oleg, Lee, Jaekwang, Jo, Seonmi, Hwang, Eun Mi, Lee, C. Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580748/
https://www.ncbi.nlm.nih.gov/pubmed/26412970
http://dx.doi.org/10.5607/en.2015.24.3.211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580748/
https://www.ncbi.nlm.nih.gov/pubmed/26412970
http://dx.doi.org/10.5607/en.2015.24.3.211

Ejemplares similares