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The Unreliability of MTT Assay in the Cytotoxic Test of Primary Cultured Glioblastoma Cells

MTT assay is commonly used to assess the cellular cytotoxicity caused by anticancer drugs in glioblastomas. However, there have been some reports insisting that MTT assay exhibited non-specific intracellular reduction of tetrazolium which led to underestimated results of cytotoxicity. Here, we exami...

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Detalles Bibliográficos
Autores principales: Jo, Hwa Yeon, Kim, Yona, Park, Hyung Woo, Moon, Hyo Eun, Bae, Seongtae, Kim, JinWook, Kim, Dong Gyu, Paek, Sun Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580751/
https://www.ncbi.nlm.nih.gov/pubmed/26412973
http://dx.doi.org/10.5607/en.2015.24.3.235