Role of T cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss

HIV infection causes bone loss. We previously reported that immunosuppression-mediated B-cell production of receptor activator of NF-κB ligand (RANKL) coupled with decline in osteoprotegerin correlate with decreased bone mineral density (BMD) in untreated HIV-infection. Paradoxically, antiretroviral...

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Detalles Bibliográficos
Autores principales: Ofotokun, Ighovwerha, Titanji, Kehmia, Vikulina, Tatyana, Roser-Page, Susanne, Yamaguchi, Masayoshi, Zayzafoon, Majd, Williams, Ifor R., Weitzmann, M. Neale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580984/
https://www.ncbi.nlm.nih.gov/pubmed/26392000
http://dx.doi.org/10.1038/ncomms9282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580984/
https://www.ncbi.nlm.nih.gov/pubmed/26392000
http://dx.doi.org/10.1038/ncomms9282

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