Cargando…
Role of T cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss
HIV infection causes bone loss. We previously reported that immunosuppression-mediated B-cell production of receptor activator of NF-κB ligand (RANKL) coupled with decline in osteoprotegerin correlate with decreased bone mineral density (BMD) in untreated HIV-infection. Paradoxically, antiretroviral...
Autores principales: | Ofotokun, Ighovwerha, Titanji, Kehmia, Vikulina, Tatyana, Roser-Page, Susanne, Yamaguchi, Masayoshi, Zayzafoon, Majd, Williams, Ifor R., Weitzmann, M. Neale |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580984/ https://www.ncbi.nlm.nih.gov/pubmed/26392000 http://dx.doi.org/10.1038/ncomms9282 |
Ejemplares similares
-
The effect of age on CD4+ T-cell recovery in HIV-suppressed adult participants: a sub-study from AIDS Clinical Trial Group (ACTG) A5321 and the Bone Loss and Immune Reconstitution (BLIR) study
por: Chen, Jingxian, et al.
Publicado: (2022) -
Dysregulated B Cell Expression of RANKL and OPG Correlates with Loss of Bone Mineral Density in HIV Infection
por: Titanji, Kehmia, et al.
Publicado: (2014) -
3159 Bone Turnover Biomarkers May Discriminate Low Bone Mineral Density in HIV-Infected Adults
por: Collins, Lauren Frances, et al.
Publicado: (2019) -
Cyclic Adenosine Monophosphate (cAMP)‐Dependent Phosphodiesterase Inhibition Promotes Bone Anabolism Through CD8
(+) T Cell Wnt‐10b Production in Mice
por: Roser‐Page, Susanne, et al.
Publicado: (2022) -
B Cell Production of Both OPG and RANKL is Significantly Increased in Aged Mice
por: Li, Yan, et al.
Publicado: (2014)