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Calcium ions open a selectivity filter gate during activation of the MthK potassium channel

Ion channel opening and closing are fundamental to cellular signalling and homeostasis. Gates that control K(+) channel activity were found both at an intracellular pore constriction and within the selectivity filter near the extracellular side but the specific location of the gate that opens Ca(2+)...

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Detalles Bibliográficos
Autores principales: Posson, David J., Rusinova, Radda, Andersen, Olaf S., Nimigean, Crina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580985/
https://www.ncbi.nlm.nih.gov/pubmed/26395539
http://dx.doi.org/10.1038/ncomms9342