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Deciphering targeting rules of splicing modulator compounds: case of TG003
BACKGROUND: Recent advances in the development of small chemical compounds that can modulate RNA splicing brought excitement to the field of splicing-targeting therapy. Splicing-targeting therapy tries to ameliorate the disease by altering the exon combination of transcripts to reduce the undesired...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580995/ https://www.ncbi.nlm.nih.gov/pubmed/26400733 http://dx.doi.org/10.1186/s12867-015-0044-6 |