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Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis

Whales have 1000-fold more cells than humans and mice have 1000-fold fewer; however, cancer risk across species does not increase with the number of somatic cells and the lifespan of the organism. This observation is known as Peto's paradox. How much would evolution have to change the parameter...

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Detalles Bibliográficos
Autores principales: Caulin, Aleah F., Graham, Trevor A., Wang, Li-San, Maley, Carlo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581027/
https://www.ncbi.nlm.nih.gov/pubmed/26056366
http://dx.doi.org/10.1098/rstb.2014.0222