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A metabolic perspective of Peto's paradox and cancer

The frequency of cancer is postulated to be proportional to the number of cells an animal possesses, as each cell is similarly exposed to mutagens with every cell division. Larger animals result from more cell divisions with more mutagenic exposure, and hence are expected to have higher frequencies...

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Detalles Bibliográficos
Autor principal: Dang, Chi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581028/
https://www.ncbi.nlm.nih.gov/pubmed/26056367
http://dx.doi.org/10.1098/rstb.2014.0223