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A metabolic perspective of Peto's paradox and cancer
The frequency of cancer is postulated to be proportional to the number of cells an animal possesses, as each cell is similarly exposed to mutagens with every cell division. Larger animals result from more cell divisions with more mutagenic exposure, and hence are expected to have higher frequencies...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581028/ https://www.ncbi.nlm.nih.gov/pubmed/26056367 http://dx.doi.org/10.1098/rstb.2014.0223 |