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Expression profiling of O(6) methylguanine-DNA-methyl transferase in prolactinomas: a correlative study of promoter methylation and pathological features in 136 cases

BACKGROUND: Low-level expression of O(6) methylguanine-DNA-methyl transferase (MGMT) prolactinomas has been noted previously in case reports, although what modulates MGMT expression remains unclear. This study therefore aimed to delineate the factors regulating MGMT expression in prolactinomas. METH...

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Detalles Bibliográficos
Autores principales: Jiang, Xiao-Bing, Hu, Bin, He, Dong-Sheng, Mao, Zhi-Gang, Wang, Xin, Song, Bing-Bing, Zhu, Yong-Hong, Wang, Hai-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581044/
https://www.ncbi.nlm.nih.gov/pubmed/26400193
http://dx.doi.org/10.1186/s12885-015-1595-0