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Expression profiling of O(6) methylguanine-DNA-methyl transferase in prolactinomas: a correlative study of promoter methylation and pathological features in 136 cases
BACKGROUND: Low-level expression of O(6) methylguanine-DNA-methyl transferase (MGMT) prolactinomas has been noted previously in case reports, although what modulates MGMT expression remains unclear. This study therefore aimed to delineate the factors regulating MGMT expression in prolactinomas. METH...
Autores principales: | Jiang, Xiao-Bing, Hu, Bin, He, Dong-Sheng, Mao, Zhi-Gang, Wang, Xin, Song, Bing-Bing, Zhu, Yong-Hong, Wang, Hai-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581044/ https://www.ncbi.nlm.nih.gov/pubmed/26400193 http://dx.doi.org/10.1186/s12885-015-1595-0 |
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