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Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases
BACKGROUND: The transcriptional repressor promyelocytic leukemia zinc finger protein (PLZF) is critical for the regulation of normal stem cells maintenance by establishing specific epigenetic landscape. We have previously shown that CBP/p300 acetyltransferase induces PLZF acetylation in order to inc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581162/ https://www.ncbi.nlm.nih.gov/pubmed/26405459 http://dx.doi.org/10.1186/s13072-015-0030-8 |