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Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases

BACKGROUND: The transcriptional repressor promyelocytic leukemia zinc finger protein (PLZF) is critical for the regulation of normal stem cells maintenance by establishing specific epigenetic landscape. We have previously shown that CBP/p300 acetyltransferase induces PLZF acetylation in order to inc...

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Detalles Bibliográficos
Autores principales:	McConnell, Melanie J., Durand, Laetitia, Langley, Emma, Coste-Sarguet, Lise, Zelent, Arthur, Chomienne, Christine, Kouzarides, Tony, Licht, Jonathan D., Guidez, Fabien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581162/ https://www.ncbi.nlm.nih.gov/pubmed/26405459 http://dx.doi.org/10.1186/s13072-015-0030-8

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