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Combination of Aβ Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC

Repair of oxidative DNA damage, particularly Base Excision Repair (BER), impairment is often associated with Alzheimer’s disease pathology. Here, we aimed at investigating the complete Nucleotide Excision Repair (NER), a DNA repair pathway involved in the removal of bulky DNA adducts, status in an A...

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Detalles Bibliográficos
Autores principales: Forestier, Anne, Douki, Thierry, De Rosa, Viviana, Béal, David, Rachidi, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581200/
https://www.ncbi.nlm.nih.gov/pubmed/26263968
http://dx.doi.org/10.3390/ijms160817422