RNase L Cleavage Products Promote Switch from Autophagy to Apoptosis by Caspase-Mediated Cleavage of Beclin-1

Autophagy and apoptosis share regulatory molecules enabling crosstalk in pathways that affect cellular homeostasis including response to viral infections and survival of tumor cells. Ribonuclease L (RNase L) is an antiviral endonuclease that is activated in virus-infected cells and cleaves viral and...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mohammad Adnan, Mukherjee, Sushovita, Manivannan, Praveen, Malathi, Krishnamurthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581211/
https://www.ncbi.nlm.nih.gov/pubmed/26263979
http://dx.doi.org/10.3390/ijms160817611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581211/
https://www.ncbi.nlm.nih.gov/pubmed/26263979
http://dx.doi.org/10.3390/ijms160817611

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