2,6-Bis(1,4,7,10-tetraazacyclododecan-1-ylmethyl)pyridine and Its Benzene Analog as Nonmetallic Cleaving Agents of RNA Phosphodiester Linkages

2,6-Bis(1,4,7,10-tetraazacyclododecan-1-ylmethyl)pyridine (11a) and 1,3-bis(1,4,7,10-tetraazacyclododecan-1-ylmethyl)benzene (11b) have been shown to accelerate at 50 mmol·L(−1) concentration both the cleavage and mutual isomerization of uridylyl-3′,5′-uridine and uridylyl-2′,5′-uridine by up to two...

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Detalles Bibliográficos
Autores principales: Lain, Luigi, Lahdenpohja, Salla, Lönnberg, Harri, Lönnberg, Tuomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581222/
https://www.ncbi.nlm.nih.gov/pubmed/26247935
http://dx.doi.org/10.3390/ijms160817798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581222/
https://www.ncbi.nlm.nih.gov/pubmed/26247935
http://dx.doi.org/10.3390/ijms160817798

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