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Conformational Motions and Functionally Key Residues for Vitamin B12 Transporter BtuCD–BtuF Revealed by Elastic Network Model with a Function-Related Internal Coordinate

BtuCD–BtuF from Escherichia coli is a binding protein-dependent adenosine triphosphate (ATP)-binding cassette (ABC) transporter system that uses the energy of ATP hydrolysis to transmit vitamin B12 across cellular membranes. Experimental studies have showed that during the transport cycle, the trans...

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Detalles Bibliográficos
Autores principales: Su, Ji-Guo, Zhang, Xiao, Zhao, Shu-Xin, Li, Xing-Yuan, Hou, Yan-Xue, Wu, Yi-Dong, Zhu, Jian-Zhuo, An, Hai-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581229/
https://www.ncbi.nlm.nih.gov/pubmed/26247943
http://dx.doi.org/10.3390/ijms160817933