The Histone Deacetylase Inhibitor BML-210 Influences Gene and Protein Expression in Human Promyelocytic Leukemia NB4 Cells via Epigenetic Reprogramming

Today, cancer is understood as an epigenetic as well as genetic disease. The main epigenetic hallmarks of the cancer cell are DNA methylation and histone modifications. Proteins such as histone deacetylases (HDACs) that cause modifications of histones and other proteins can be targets for novel anti...

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Detalles Bibliográficos
Autores principales: Borutinskaitė, Veronika, Navakauskienė, Rūta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581243/
https://www.ncbi.nlm.nih.gov/pubmed/26287160
http://dx.doi.org/10.3390/ijms160818252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581243/
https://www.ncbi.nlm.nih.gov/pubmed/26287160
http://dx.doi.org/10.3390/ijms160818252

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