Potential Effects of Phytoestrogen Genistein in Modulating Acute Methotrexate Chemotherapy-Induced Osteoclastogenesis and Bone Damage in Rats

Chemotherapy-induced bone damage is a frequent side effect which causes diminished bone mineral density and fracture in childhood cancer sufferers and survivors. The intensified use of anti-metabolite methotrexate (MTX) and other cytotoxic drugs has led to the need for a mechanistic understanding of...

Descripción completa

Detalles Bibliográficos
Autores principales: King, Tristan J., Shandala, Tetyana, Lee, Alice M., Foster, Bruce K., Chen, Ke-Ming, Howe, Peter R., Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581246/
https://www.ncbi.nlm.nih.gov/pubmed/26258775
http://dx.doi.org/10.3390/ijms160818293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581246/
https://www.ncbi.nlm.nih.gov/pubmed/26258775
http://dx.doi.org/10.3390/ijms160818293

Ejemplares similares