SCM-198 Ameliorates Cognitive Deficits, Promotes Neuronal Survival and Enhances CREB/BDNF/TrkB Signaling without Affecting Aβ Burden in AβPP/PS1 Mice

SCM-198 is an alkaloid found only in Herba leonuri and it has been reported to possess considerable neuroprotective effects in animal models of ischemic stroke, Parkinson’s disease and Alzheimer’s disease (AD). In this study, we demonstrated for the first time that 3-month oral SCM-198 treatment cou...

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Detalles Bibliográficos
Autores principales: Hong, Zhen-Yi, Yu, Shuang-Shuang, Wang, Zhi-Jun, Zhu, Yi-Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581259/
https://www.ncbi.nlm.nih.gov/pubmed/26262618
http://dx.doi.org/10.3390/ijms160818544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581259/
https://www.ncbi.nlm.nih.gov/pubmed/26262618
http://dx.doi.org/10.3390/ijms160818544

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