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ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder that affects upper and lower motor neurons. Since motor neurons target skeletal muscles, the maintenance system of muscles is disturbed in ALS; however, the mechanism by which this occurs is unknown. In the prese...

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Detalles Bibliográficos
Autores principales: Tokutake, Yukako, Yamada, Keita, Ohata, Masaki, Obayashi, Yoshihito, Tsuchiya, Megumi, Yonekura, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581263/
https://www.ncbi.nlm.nih.gov/pubmed/26266407
http://dx.doi.org/10.3390/ijms160818628