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In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats
Polyglutamine diseases, including Huntington’s disease and a number of spinocerebellar ataxias, are caused by expanded CAG repeats that are located in translated sequences of individual, functionally-unrelated genes. Only mutant proteins containing polyglutamine expansions have long been thought to...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581269/ https://www.ncbi.nlm.nih.gov/pubmed/26270660 http://dx.doi.org/10.3390/ijms160818741 |