Fumaric Acid Esters Do Not Reduce Inflammatory NF-κB/p65 Nuclear Translocation, ICAM-1 Expression and T-Cell Adhesiveness of Human Brain Microvascular Endothelial Cells

Dimethyl fumarate (DMF) is approved for disease-modifying treatment of patients with relapsing-remitting multiple sclerosis. Animal experiments suggested that part of its therapeutic effect is due to a reduction of T-cell infiltration of the central nervous system (CNS) by uncertain mechanisms. Here...

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Detalles Bibliográficos
Autores principales: Haarmann, Axel, Nehen, Mathias, Deiß, Annika, Buttmann, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581287/
https://www.ncbi.nlm.nih.gov/pubmed/26287168
http://dx.doi.org/10.3390/ijms160819086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581287/
https://www.ncbi.nlm.nih.gov/pubmed/26287168
http://dx.doi.org/10.3390/ijms160819086

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