Lentiviral-Mediated Short Hairpin RNA Knockdown of MTDH Inhibits Cell Growth and Induces Apoptosis by Regulating the PTEN/AKT Pathway in Hepatocellular Carcinoma

The activation of oncogenes and the loss of tumor suppressor genes are believed to play critical roles in the pathogenesis of human hepatocellular carcinoma (HCC). Metaherin (MTDH), also called astrocyte elevated gene-1 (AEG-1), is frequently amplified in a variety of cancers, but the roles of MTDH...

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Detalles Bibliográficos
Autores principales: Li, Wen-Fang, Ou, Qin, Dai, Hang, Liu, Chang-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581304/
https://www.ncbi.nlm.nih.gov/pubmed/26287185
http://dx.doi.org/10.3390/ijms160819419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581304/
https://www.ncbi.nlm.nih.gov/pubmed/26287185
http://dx.doi.org/10.3390/ijms160819419

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