Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma

Mutations in Human Epidermal Growth Factor Receptors (HER) are associated with poor prognosis of several types of solid tumors. Although HER-mutation detection methods are currently available, such as Next-Generation Sequencing (NGS), alternative pyrosequencing allow the rapid characterization of sp...

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Detalles Bibliográficos
Autores principales: González-Alonso, Paula, Chamizo, Cristina, Moreno, Víctor, Madoz-Gúrpide, Juan, Carvajal, Nerea, Daoud, Lina, Zazo, Sandra, Martín-Aparicio, Ester, Cristóbal, Ion, Rincón, Raúl, García-Foncillas, Jesús, Rojo, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581306/
https://www.ncbi.nlm.nih.gov/pubmed/26287187
http://dx.doi.org/10.3390/ijms160819447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581306/
https://www.ncbi.nlm.nih.gov/pubmed/26287187
http://dx.doi.org/10.3390/ijms160819447

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