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Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma
Mutations in Human Epidermal Growth Factor Receptors (HER) are associated with poor prognosis of several types of solid tumors. Although HER-mutation detection methods are currently available, such as Next-Generation Sequencing (NGS), alternative pyrosequencing allow the rapid characterization of sp...
Autores principales: | González-Alonso, Paula, Chamizo, Cristina, Moreno, Víctor, Madoz-Gúrpide, Juan, Carvajal, Nerea, Daoud, Lina, Zazo, Sandra, Martín-Aparicio, Ester, Cristóbal, Ion, Rincón, Raúl, García-Foncillas, Jesús, Rojo, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581306/ https://www.ncbi.nlm.nih.gov/pubmed/26287187 http://dx.doi.org/10.3390/ijms160819447 |
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