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Mitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?

Mitochondrial dysfunction and impairment of the ubiquitin proteasome system have been described as two hallmarks of the ageing process. Additionally, both systems have been implicated in the etiopathogenesis of many age-related diseases, particularly neurodegenerative disorders, such as Alzheimer’s...

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Detalles Bibliográficos
Autores principales: Ross, Jaime M., Olson, Lars, Coppotelli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581307/
https://www.ncbi.nlm.nih.gov/pubmed/26287188
http://dx.doi.org/10.3390/ijms160819458