One-Pot Cannizzaro Cascade Synthesis of ortho-Fused Cycloocta-2,5-dien-1-ones from 2-Bromo(hetero)aryl Aldehydes

An intramolecular Cannizzaro-type hydride transfer to an in situ prepared allene enables the synthesis of ortho-fused 4-substituted cycloocta-2,5-dien-1-ones with unprecedented technical ease for an eight-ring carboannulation. Various derivatives could be obtained from commercially available (hetero...

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Detalles Bibliográficos
Autores principales: Burroughs, Laurence, Eccleshare, Lee, Ritchie, John, Kulkarni, Omkar, Lygo, Barry, Woodward, Simon, Lewis, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581465/
https://www.ncbi.nlm.nih.gov/pubmed/26230528
http://dx.doi.org/10.1002/anie.201505347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581465/
https://www.ncbi.nlm.nih.gov/pubmed/26230528
http://dx.doi.org/10.1002/anie.201505347

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