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Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(–/–) Mice

[Image: see text] The current study presents an effective and selective multifunctional nanoparticle used to deliver antiatherogenic therapeutics to inflamed pro-atherogenic regions without off-target changes in gene expression or particle-induced toxicities. MicroRNAs (miRNAs) regulate gene express...

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Detalles Bibliográficos
Autores principales: Kheirolomoom, Azadeh, Kim, Chan Woo, Seo, Jai Woong, Kumar, Sandeep, Son, Dong Ju, Gagnon, M. Karen J., Ingham, Elizabeth S., Ferrara, Katherine W., Jo, Hanjoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581466/
https://www.ncbi.nlm.nih.gov/pubmed/26308181
http://dx.doi.org/10.1021/acsnano.5b02611