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Efficient Mitochondrial Genome Editing by CRISPR/Cas9

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system has been widely used for nuclear DNA editing to generate mutations or correct specific disease alleles. Despite its flexible application, it has not been determined if CRISPR/Cas9, originally identified as a bacterial...

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Detalles Bibliográficos
Autores principales: Jo, Areum, Ham, Sangwoo, Lee, Gum Hwa, Lee, Yun-Il, Kim, SangSeong, Lee, Yun-Song, Shin, Joo-Ho, Lee, Yunjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581504/
https://www.ncbi.nlm.nih.gov/pubmed/26448933
http://dx.doi.org/10.1155/2015/305716