Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy

Myostatin is a secreted signaling molecule that normally acts to limit muscle growth. As a result, there is extensive effort directed at developing drugs capable of targeting myostatin to treat patients with muscle loss. One potential concern with this therapeutic approach in patients with muscle de...

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Detalles Bibliográficos
Autores principales: Lee, Yun-Sil, Lehar, Adam, Sebald, Suzanne, Liu, Min, Swaggart, Kayleigh A., Talbot, C. Conover, Pytel, Peter, Barton, Elisabeth R., McNally, Elizabeth M., Lee, Se-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581601/
https://www.ncbi.nlm.nih.gov/pubmed/26206886
http://dx.doi.org/10.1093/hmg/ddv288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581601/
https://www.ncbi.nlm.nih.gov/pubmed/26206886
http://dx.doi.org/10.1093/hmg/ddv288

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