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Muscle hypertrophy induced by myostatin inhibition accelerates degeneration in dysferlinopathy
Myostatin is a secreted signaling molecule that normally acts to limit muscle growth. As a result, there is extensive effort directed at developing drugs capable of targeting myostatin to treat patients with muscle loss. One potential concern with this therapeutic approach in patients with muscle de...
Autores principales: | Lee, Yun-Sil, Lehar, Adam, Sebald, Suzanne, Liu, Min, Swaggart, Kayleigh A., Talbot, C. Conover, Pytel, Peter, Barton, Elisabeth R., McNally, Elizabeth M., Lee, Se-Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581601/ https://www.ncbi.nlm.nih.gov/pubmed/26206886 http://dx.doi.org/10.1093/hmg/ddv288 |
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