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Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing

Precise delineation of the specific genes and pathways altered with aging and estrogen (E) therapy may lead to new skeletal biomarkers and the development of novel bone therapeutics. Previous human bone studies, however, have been limited by only examining pre-specified genes and pathways. High-thro...

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Detalles Bibliográficos
Autores principales: Farr, Joshua N., Roforth, Matthew M., Fujita, Koji, Nicks, Kristy M., Cunningham, Julie M., Atkinson, Elizabeth J., Therneau, Terry M., McCready, Louise K., Peterson, James M., Drake, Matthew T., Monroe, David G., Khosla, Sundeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581624/
https://www.ncbi.nlm.nih.gov/pubmed/26402159
http://dx.doi.org/10.1371/journal.pone.0138347